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Writer's picturePauleen Flake, RND

Orlistat for Weight Loss: 5 Facts You Shouldn't Overlook


If you're struggling to lose weight through diet and exercise alone, Orlistat may be the solution you're looking for. This medication is specifically designed to block the absorption of dietary fat, making it an effective tool for weight loss. But before you start taking Orlistat, it's important to know what you're getting into. That's why we've put together a list of five essential facts about this medication that you need to know. From its brand names to its effectiveness, potential side effects, and more, this guide will give you a comprehensive overview of what Orlistat is all about. So, whether you're considering Orlistat as a weight loss option or you're simply curious about how it works, read on to discover everything you need to know!


What is Orlistat?

Orlistat is a medication used to aid weight loss by blocking the absorption of dietary fat. Remember that before using this weight loss medicine to consult first with a weight loss specialist to better understand your options. Here are five facts about Orlistat that you should know:


What’s in a Name?


Orlistat, the active ingredient in weight loss medication, is marketed under different brand names depending on the country where it is sold. The generic name for Orlistat is simply "Orlistat," but it is known by various brand names, such as Xenical, Alli, Orlos, and Olistat.


Xenical, which is the brand name of Orlistat in the United States, is a prescription medication that is typically used for weight management in individuals with a body mass index (BMI) of 30 or higher. It is also prescribed for individuals with a BMI of 27 or higher who have other health risks, such as high blood pressure, diabetes, or high cholesterol.


Alli, on the other hand, is the brand name for Orlistat that is sold over the counter in the United States. It is available without a prescription and is typically used in conjunction with a reduced-calorie, low-fat diet, and regular exercise to help people lose weight.


In other countries, Orlistat is marketed under different brand names. It's important to note that although Orlistat may be marketed under different brand names, the active ingredient remains the same, and it works in the same way to block the absorption of dietary fat.



Photo From: Dr. Fox

It Blocks Quick


Orlistat is a weight loss medication that works by blocking the absorption of dietary fat in the body. It does this by inhibiting the action of an enzyme called lipase, which is responsible for breaking down dietary fat in the small intestine. When lipase is blocked, the body is unable to absorb up to 30% of the dietary fat that is consumed. This means that fewer calories from fat are absorbed by the body, which can lead to weight loss.


It's worth noting that Orlistat does not block the absorption of all types of fat in the diet. It specifically blocks the absorption of triglycerides, which are the most common type of fat found in food. Orlistat does not affect the absorption of carbohydrates or proteins.


No Magic Here!


Orlistat is a medication that works by inhibiting the enzymes in the digestive system that break down fat. This means that when you take Orlistat, your body is less able to absorb the fat you consume. However, this doesn't mean that you can eat a high-fat diet and still lose weight.


To achieve the best results with Orlistat, it is important to follow a low-fat diet while taking the medication. This means consuming foods that are low in fat, such as fruits, vegetables, lean proteins, and whole grains. You should aim to limit your fat intake to no more than 30% of your daily calories.


It is also important to note that Orlistat is not a magic pill that will help you lose weight on its own. It should be used as part of a comprehensive weight-loss plan that includes a healthy diet and regular exercise. When used in combination with these lifestyle changes, Orlistat can help you achieve your weight loss goals.





Win Some, Lose Some

Orlistat can be an effective tool for weight loss when used in conjunction with a low-fat diet and exercise, but it is important to be aware of the potential side effects and risks associated with this medication. One of the most significant risks is the potential for nutrient deficiencies.


Because Orlistat blocks the absorption of dietary fat, it can also interfere with the absorption of fat-soluble vitamins such as vitamins A, D, E, and K. These vitamins are important for maintaining healthy bones, skin, eyes, and immune function. Over time, a deficiency in these vitamins can lead to a range of health problems, including osteoporosis, anemia, and impaired immune function.


To reduce the risk of nutrient deficiencies, people taking Orlistat are advised to take a multivitamin supplement that contains these vitamins. It is also recommended to take the supplement at least two hours before or after taking Orlistat, as the medication can interfere with the absorption of the vitamins.


It’s Legit.

Orlistat is a medication that is commonly used to aid weight loss. It works by blocking the absorption of fat in the intestines, thereby reducing the number of calories that the body can extract from food. When used in conjunction with a low-fat diet, Orlistat has been clinically proven to aid weight loss.


Numerous clinical studies have been conducted to evaluate the efficacy of Orlistat in promoting weight loss. These studies have consistently shown that people who take Orlistat in conjunction with a low-fat diet lose more weight than those who only follow a low-fat diet.


The most well-known study is the Swedish XENDOS study, which involved 3,305 people with obesity and lasted for 4 years. Participants were divided into two groups, one taking 120 mg of orlistat three times daily and the other taking a placebo. Both groups were instructed to eat 800 fewer calories per day than needed to maintain their current weight and limit dietary fat to 30% of calories while engaging in daily exercise.


What are the Side Effects of Orlistat?

  1. Digestive symptoms: Orlistat medications block fat absorption which may lead to undigested fat in the bowel causing digestive symptoms like abdominal pain, diarrhea, and flatulence. Fecal incontinence and oily stools are also possible side effects.

  2. Impaired nutrient absorption: Long-term use of Orlistat can result in impaired absorption of fat-soluble nutrients like vitamins A, D, E, and K and calcium. Taking a multivitamin is recommended but should be taken at least 2 hours apart from Orlistat.

  3. Increased risk of kidney injury: Orlistat may increase the risk of kidney injury due to the binding of unabsorbed fat with calcium in the digestive system, leading to calcium oxalate crystal deposits in the kidneys.

  4. Drug interactions: Orlistat can interfere with the absorption of some medications, including those used to treat conditions such as epilepsy, thyroid conditions, irregular heartbeat, and HIV. Consult a doctor before taking Orlistat if you're taking any medication.






Healthy Weight Loss Tips, Straight from the Experts

  • Consult a lifestyle medicine specialist or a weight loss specialist to design a customized weight loss plan that is safe and effective, taking into account any medical conditions or medications you may be taking.

  • Make dietary changes, such as reducing calorie intake, limiting consumption of processed foods and sugary drinks, and increasing intake of fruits, vegetables, and whole grains.

  • Incorporate physical activity into daily life by engaging in activities like walking, swimming, or cycling to help burn calories and promote weight loss.

  • Practice stress management techniques like meditation to aid weight loss, as stress can lead to weight gain.

  • Consider joining a weight loss support group or seeking the help of a registered dietitian or a personal trainer for motivation and guidance on safe weight loss.

  • If necessary, consult a healthcare professional about weight loss medication options, such as Orlistat, which can aid weight loss under medical supervision. However, medication should only be used as a last resort and under the guidance of a healthcare professional.

Contact a Weight Loss Specialist Right Now

If you're struggling with weight loss and need professional guidance and support, consider reaching out to a weight loss specialist or visiting a weight loss clinic. They can provide you with personalized advice, support, and treatment options to help you achieve your weight loss goals in a safe and effective manner. Don't hesitate to take the first step towards a healthier you - book an appointment with a weight loss specialist today!


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