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Writer's picturePauleen Flake, RND

10 Exciting Facts About The Hit Medicine Ozempic

Updated: May 25, 2023



Struggling with weight loss? You're not alone. For many individuals, achieving and maintaining a healthy weight can be a challenging and frustrating journey. From navigating through countless diets and exercise routines to battling with emotional and psychological barriers, the path to weight loss success can feel overwhelming.


Enter Ozempic. Ozempic, a groundbreaking weight loss medication, has been making waves in the medical field for its remarkable results. In this article, we'll delve into ten exciting facts about Ozempic, uncovering its mechanism of action, impressive weight loss outcomes, and additional benefits for cardiovascular health and metabolic parameters. We'll also explore its convenient administration method and touch upon important considerations before starting this medication. So, let's embark on this enlightening journey to discover the incredible potential of Ozempic in your weight loss journey.


10 Fascinating Ozempic Facts:

Photo by: NBC


It Goes By Another Name


Ozempic is a brand name for the medication semaglutide, which is approved by the U.S. Food and Drug Administration (FDA) for the treatment of obesity in adults.


Mimicry Is A Thing Here


Semaglutide, the active ingredient in Ozempic, is a glucagon-like peptide-1 (GLP-1) receptor agonist. It works by mimicking the action of a naturally occurring hormone in the body called GLP-1, which helps regulate appetite and food intake.


It’s Really, Really Effective


Ozempic has been shown to be highly effective in aiding weight loss. In clinical trials, people taking Ozempic in combination with diet and exercise achieved significantly greater weight loss compared to those on placebo. The weight loss achieved with Ozempic can be substantial. In one study, patients taking Ozempic lost an average of 15% of their body weight, compared to 2.4% in the placebo group.


A Wee Bit Prickly


Ozempic is administered once a week via a subcutaneous injection. The medication comes in a pre-filled pen, making it convenient and easy to use.


It's Made From Something...Different

Ozempic, a GLP-1 agonist medication, is derived from the Gila monster's venomous saliva, a lizard species inhabiting US and Mexican deserts. Research conducted by endocrinologist John Eng in 1990 explored the potential medicinal applications of both toxic and nontoxic chemicals produced by Gila monsters.


The key peptide responsible for this metabolic control is called Exendin-4, which shares remarkable similarities in structure and function with human GLP-1. As a result, Exendin-4 was developed into the first synthetic GLP-1 drug, known as Exenatide, which serves as the foundation for Ozempic.


It Won’t Break Your Heart


In addition to promoting weight loss, Ozempic has shown benefits for cardiovascular health. Studies have demonstrated a reduced risk of major adverse cardiovascular events, such as heart attack and stroke, in individuals taking Ozempic.




It Goes All In


Ozempic has also been found to improve other metabolic parameters, including blood sugar control and insulin resistance. This makes it particularly beneficial for individuals with type 2 diabetes who struggle with weight management.


Of Course, It Isn’t Without Its Struggles


The most common side effects of Ozempic include nausea, vomiting, diarrhea, and constipation. These effects are usually mild and tend to diminish over time as the body adjusts to the medication.


Like All Things, It’s Not For Everyone


Ozempic is not recommended for use in individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2). It is important to discuss any existing medical conditions with a healthcare professional before starting Ozempic.


No (Medication) One Is an Island


Ozempic should be used as part of a comprehensive weight management plan that includes a healthy diet and regular exercise. It is important to consult with a healthcare professional to determine if Ozempic is the right option for you and to receive appropriate guidance and monitoring throughout the treatment.


Confused? Here’s 5 Tips On Taking Ozempic


When is the optimal time to administer Ozempic?


It is recommended to inject Ozempic once a week, consistently on the same day of the week. The timing of the injection, whether in the morning or evening, does not significantly impact its effectiveness.


If you wish to change the day of the week for your Ozempic injection, it is advisable to consult with your healthcare provider or pharmacist beforehand. They can provide guidance to ensure a safe transition. It is generally recommended to maintain a gap of at least 2 days between injections.


When administering Ozempic, it should be injected under the skin in either the abdomen, upper arm, or thigh. To minimize the formation of scar tissue, it is important to rotate the injection sites, choosing a different location each time.


Is it necessary to take Ozempic with food?

Ozempic can be taken with or without food. Since it is administered once a week via injection, the presence or absence of food does not impact its absorption. The medication does not rely on stomach absorption.


Should Ozempic be separated from other medications?

Ozempic may interact with certain medications; however, it is not usually necessary to separate it from other medications. Many interactions can be effectively managed through dose adjustments and monitoring.


As previously mentioned, Ozempic stimulates the release of insulin in response to food intake. If you are taking Ozempic along with insulin or other insulin-releasing medications, such as sulfonylureas, it may increase the risk of hypoglycemia (low blood sugar). To avoid this, your healthcare provider may make adjustments to these medications when initiating Ozempic treatment.


Due to its effect on stomach emptying, Ozempic may potentially impact the absorption of certain oral medications. Your healthcare provider can assess if this is a concern based on your current medication list and provide appropriate guidance.


What should I do if I miss a dose of Ozempic?


If you realize that you missed a dose of Ozempic and it has been 5 days or less since the missed dose, take it as soon as you remember. However, it is important to note that this day will become your new scheduled day for future doses. Subsequently, you will administer Ozempic every 7 days based on this revised day of the week.


If more than 5 days have passed since the missed dose, it is recommended to skip the missed dose and resume the regular dosing schedule on the established day.


How should I address potential side effects from Ozempic?


Like any medication, Ozempic can cause side effects. Most side effects are manageable at home and tend to resolve over time. However, if you experience persistent or severe side effects, it is crucial to contact your healthcare provider. They can evaluate your situation and may advise discontinuing Ozempic if necessary.


The most commonly reported side effects of Ozempic are related to the stomach, including nausea, vomiting, and diarrhea. If you encounter indigestion or nausea, consuming smaller meals can be helpful.


As previously mentioned, the dosage of Ozempic is gradually increased to minimize these effects. If you find it challenging to tolerate the medication, your healthcare provider might recommend continuing with a lower dose.


Take Control of Your Health Right Now!


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